MD2-TLR4-IN-1 is a myeloid differentiation protein 2/toll-like receptor 4 (MD2-TLR4) complex antagonist. MD2-TLR4-IN-1 inhibits Lipopolysaccharides (HY-D1056) (LPS)-induced expression of TNF-alpha and IL-6 in macrophages with IC50 values of 0.89 µM and 0.53 µM, respectively. MD2-TLR4-IN-1 can be used for the study of acute lung injury (ALI)[1].
Molecular Weight:
421.28
Purity:
98.16
CAS Number:
[2249801-12-3]
Formula:
C22H14Cl2N4O
Target:
NF-kappaB,Toll-like Receptor (TLR)
Application Notes:
MCE Product type: Reference compound
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