ERD-308 is a potent estrogen receptor (ER) PROTAC degrader. ERD-308 has DC50 values of 0.17 nM and 0.43 nM in MCF-7 and T47D ER+ cells. ERD-308 can inhibit the proliferation of breast cancer cells and exhibits anti-tumor activity. (Pink: Target Protein Ligand (HY-48027), Black: Linker (HY-172643), Blue: VHL Ligand (HY-112078), VHL Ligand+Linker:(HY-172645))[1]
Molecular Weight:
1004.26
Purity:
98.13
CAS Number:
[2320561-35-9]
Formula:
C55H65N5O9S2
Target:
Estrogen Receptor/ERR,PROTACs
Application Notes:
MCE Product type: Reference compound
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