CHK1-IN-3 is a potent and selective CHK1 inhibitor with an IC50 of 0.4 nM. CHK1-IN-3 effectively inhibits the growth of malignant hematopathy cell lines and displays low affinity for hERG (IC50 > 40 µM). CHK1-IN-3 significantly suppresses the tumor growth in vivo. CHK1-IN-3 can be used for the study of hematologic malignancies[1].
Molecular Weight:
405.46
Purity:
99.79
CAS Number:
[2097252-39-4]
Formula:
C20H23N9O
Target:
Checkpoint Kinase (Chk)
Application Notes:
MCE Product type: Reference compound
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