Larotrectinib (LOXO-101) is an ATP-competitive oral, selective inhibitor of the tropomyosin-related kinase (TRK) family receptors, with low nanomolar 50% inhibitory concentrations against all three isoforms (TRKA, B, and C).
Molecular Weight:
428.44
Purity:
99.93
CAS Number:
[1223403-58-4]
Formula:
C21H22F2N6O2
Target:
Apoptosis,Trk Receptor
Application Notes:
Reference compound
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