Foropafant (SR27417) highly potent, competitive, selective and orally active antagonist of platelet-activating factor (PAF) receptor, with a Ki value of 57 pM for [3H]PAF binding, at least 5-fold lower than that of unlabeled PAF itself. Foropafant potently inhibits PAF-induced aggregation of rabbit and human platelets[1].
Molecular Weight:
464.72
Purity:
99.97
CAS Number:
[136468-36-5]
Formula:
C28H40N4S
Target:
Platelet-activating Factor Receptor (PAFR)
Application Notes:
Reference compound
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