CHK1-IN-4 is a selective checkpoint kinase 1 (Chk1) inhibitor with an IC50 1 nM. The IC50 value of CHK1-IN-4 against Chk2 ranges from 50 to 100 nM. CHK1-IN-4 inhibits cancer cell proliferation and exhibits antitumor activity in colon cancer xenograft models. CHK1-IN-4 can be used for the research of colon cancer and breast cancer[1].
Molecular Weight:
444.29
CAS Number:
[2120398-41-4]
Formula:
C18H18BrN7O2
Target:
Checkpoint Kinase (Chk)
Application Notes:
MCE Product type: Reference compound
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