ddhCTP (trisodium) solution (100 mM) Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-128788A
Supplier Catalog Number:
HY-128788A
Alternative Catalog Number:
MCE-HY-128788A-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
ddhCTP trisodium solution (100 mM) is an endogenously produced pyrimidine base analog with a Kd of 17.0 nM for LLDH and an IC50 of 55.8 µM for GAPDH. By inhibiting key metabolic enzymes such as GAPDH, ddhCTP trisodium reduces glycolytic flux and shifts metabolic flow toward the pentose phosphate pathway, thereby regulating the redox balance of cells. As a competitive CTP analog, ddhCTP trisodium terminates RNA synthesis by flavivirus RdRps and SARS-CoV-2 RdRp, and inhibits Zika virus replication in vivo. ddhCTP trisodium can be used in studies related to viral infections, COVID-19 and Zika virus infections[1][2].
