PROTAC CRBN Degrader-1 (Compound 14a) is a VHL-CRBN heterodimerization PROTAC degrader that achieves a selective degradation of CRBN by binding two E3 ubiquitin ligases (VHL and CRBN) to each other[1]. (Blue: VHL ligand (S,R,S)-AHPC (HY-125845), Pink: CRBN ligand Pomalidomide-C2-NH2 (HY-128846), Black: Linker (HY-128847))
Molecular Weight:
1061.25
Purity:
99.84
CAS Number:
[2358775-70-7]
Formula:
C53H72N8O13S
Target:
E1/E2/E3 Enzyme,PROTACs
Application Notes:
Reference compound
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