VP3.15 is a potent, orally bioavailable and CNS-penetrant dual phosphodiesterase (PDE)7- glycogen synthase kinase (GSK)3 inhibitor, with IC50s of 1.59 µM and 0.88 µM for PDE7 and GSK-3, respectively. VP3.15 has neuroprotective and neuroreparative activities, thus as potential combined anti-inflammatory and pro-remyelinating therapies for multiple sclerosis (MS)[1].
Molecular Weight:
366.48
CAS Number:
[1281681-54-6]
Formula:
C20H22N4OS
Target:
GSK-3,Phosphodiesterase (PDE)
Application Notes:
MCE Product type: Reference compound
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