MAC glucuronide phenol-linked SN-38 is a pH-susceptible lactone MAC glucuronide phenol-linked SN-38 (DNA topoisomerase I inhibitor) agent linker. MAC glucuronide phenol-linked SN-38 is cytotoxic across L540cy cells and Ramos cells with IC50 values of 113 and 67 ng/mL, respectively.Albumin-coupled MAC glucosidol-linked SN-38 shows good stability in mouse plasma[1][2].
Molecular Weight:
1091.06
Purity:
99.50
CAS Number:
[2246380-69-6]
Formula:
C50H54N6O20S
Target:
Drug-Linker Conjugates for ADC
Application Notes:
MCE Product type: ADC Related
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