CL2A is a claevable complicated PEG8- and triazole-containing PABC-peptide-mc linker. CL2A is cleavable through pH sensitivity, giving rise to bystander effect, and binds the antibody at a cysteine residue via a disulfide bond. Labetuzumab govitecan used this linker[1].
Molecular Weight:
1062.21
Purity:
98.20
CAS Number:
[2616704-22-2]
Formula:
C50H79N9O16
Target:
ADC Linker
Application Notes:
MCE Product type: ADC Related
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