CL2A TFA is a claevable complicated PEG8- and triazole-containing PABC-peptide-mc linker. CL2A TFA is cleavable through pH sensitivity, giving rise to bystander effect, and binds the antibody at a cysteine residue via a disulfide bond. Labetuzumab govitecan used this linker[1].
Molecular Weight:
1176.24
Purity:
99.49
Formula:
C52H80F3N9O18
Target:
ADC Linker
Application Notes:
MCE Product type: ADC Related
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