ML318 is a biaryl nitrile inhibitor of PvdQ acylase with an IC50 of 20 nM by binding in the acyl-binding site. ML318 inhibits P. aeruginosa (PAO1) with an IC50 of 19 µM. ML318 prevents pyoverdine production and limits the growth of P. aeruginosa under iron-limiting conditions[1].
Molecular Weight:
280.22
Purity:
99.26
CAS Number:
[1610516-67-0]
Formula:
C14H8F4N2
Target:
Antibiotic
Application Notes:
MCE Product type: Reference compound
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