V116517 is a potent, orally active transient receptor potential vanilloid (TRPV1) antagonist. V116517 shows potent activity in inhibiting both capsaicin (CAP)- and acid (pH 5)-induced currents in rat DRG neurons expressing native TRPV (IC50=423.2 nM for CAP, IC50=180.3 nM for acid). V116517 can be used for the research of pain[1].
Molecular Weight:
442.82
CAS Number:
[1073616-61-1]
Formula:
C19H18ClF3N4O3
Target:
TRP Channel
Application Notes:
MCE Product type: Reference compound
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