KMUP-4, as a xanthine derivative with cGMP-enhancing activity, induces aortic relaxation through endothelium-dependent and independent mechanisms. KMUP-4 increases cytoplasmic cyclic guanosine monophosphate (cGMP) and cyclic adenosine monophosphate (cAMP) levels by inhibiting phosphodiesterases (PDEs) and activating K+ channels. KMUP-4 can be used in the study of cardiovascular diseases[1].
Molecular Weight:
413.43
CAS Number:
[864873-81-4]
Formula:
C19H23N7O4
Target:
Phosphodiesterase (PDE),Potassium Channel
Application Notes:
MCE Product type: Reference compound
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