SPR719 (VXc-486) is an orally active gyrase B inhibitor, with bactericidal activity. SPR719 potently inhibits multiple agent-sensitive isolates and drug-resistant isolates of Mycobacterium tuberculosis, with MICs of 0.03 to 0.30 µg/ml and 0.08 to 5.48 µg/ml, respectively. SPR719 is promising for research of lung disease caused by non-tuberculous mycobacteria (NTM)[1][2][3][4].
Molecular Weight:
428.46
Purity:
99.39
CAS Number:
[1384984-18-2]
Formula:
C21H25FN6O3
Target:
Bacterial,Topoisomerase
Application Notes:
MCE Product type: Reference compound
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