A457 is a prokineticin receptor PKR2 antagonist, with an IC50 of 102 nM. A457 can rescue the cell surface expression and function of P290S PKR2, but not W178S and G234D PKR2[1].
Molecular Weight:
457.00
CAS Number:
[1233923-95-9]
Formula:
C26H33ClN2O3
Target:
Prokineticin Receptor
Application Notes:
MCE Product type: Reference compound
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