AS-183 is an inhibitor of cholesterol acyltransferase (ACAT) (IC50=0.94 µM). AS-183 also inhibits the formation of cholesterol esters in HepG2, CaCo2 and THP-1 cells with IC50 values of 18.1, 25.5 and 34.5 µM, respectively. AS-183 can be used in the study of atherosclerosis and hypercholesterolemia[1].
Molecular Weight:
310.47
CAS Number:
[147317-12-2]
Formula:
C19H34O3
Target:
Acyltransferase
Application Notes:
MCE Product type: Natural Products
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