DC0-NH2 is an effector moiety for ADC and a simplified analog of DC1 with better stability. DC0-NH2 is about 1000-fold more cytotoxic than commonly used anticancer agents (ex. Doxorubicin). DC0-NH2 can bind to the minor groove of DNA, followed by alkylation of adenine residues by its propabenzindole (CBI) component[1].
Molecular Weight:
550.01
Purity:
95.00
CAS Number:
[615538-51-7]
Formula:
C31H24ClN5O3
Target:
ADC Payload
Application Notes:
MCE Product type: ADC Related
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