Pulrodemstat (CC-90011) hydrochloride is a potent, selective, reversible and orally active inhibitor of lysine specific demethylase-1 (LSD1) with an IC50 value of 0.25 nM. Pulrodemstat hydrochloride is less enzymatic inhibition against LSD2, MOA-A, and MAO-B. Pulrodemstat hydrochloride induces acute myeloid leukemia (AML) and small cell lung cancer (SCLC) cells differentiation and has potent anticancer activity[1].
Molecular Weight:
487.93
CAS Number:
[1821307-11-2]
Formula:
C24H24ClF2N5O2
Target:
Histone Demethylase
Application Notes:
MCE Product type: Reference compound
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