RO4583298 is a potent, orally active dual antagonist of NK1 (human and gerbil)/NK3 (human, cynomolgus monkey, gerbil and guinea-pig). RO4583298 inhibits senktide-induced potentiation of spontaneous activity of dopaminergic neurons. RO4583298 can block gerbil foot tapping response and inhibits mouse tail whips[1].
Molecular Weight:
613.57
CAS Number:
[825643-56-9]
Formula:
C30H30F7N3O3
Target:
Neurokinin Receptor
Application Notes:
MCE Product type: Reference compound
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