O-Desmethyl Midostaurin (CGP62221, O-Desmethyl PKC412) is the active metabolite of Midostaurin (HY-10230) via cytochrome P450 liver enzyme metabolism. O-Desmethyl Midostaurin can be used as an indicator for Midostaurin metabolism in vivo[1]. Midostaurin is a multi-targeted protein kinase inhibitor with IC50 ranging from 22-500 nM.
Molecular Weight:
556.61
Purity:
97.08
CAS Number:
[740816-86-8]
Formula:
C34H28N4O4
Target:
PKC
Application Notes:
MCE Product type: Reference compound1
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