L-2286 is an orally active PARP-1 inhibitor. L-2286 alleviates carotid artery remodeling, oxidative stress and inflammation in spontaneously hypertensive rats, protects neurons in the dorsal hippocampus, and reduces pyramidal cell loss and gliosis without affecting blood pressure. L-2286 can be used in research related to hypertension[1].
Molecular Weight:
289.40
CAS Number:
[684276-17-3]
Formula:
C15H19N3OS
Target:
NF-kappaB,PARP
Application Notes:
MCE Product type: Reference compound
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