SKLB4771 is a potent and selective Flt3 inhibitor with an IC50 value of 10 nM. SKLB4771 downregulates the phosphorylation of FLT3/STAT5/ERK, blocks cell proliferation, and induces apoptosis in tumor tissue[1][2].
Molecular Weight:
537.66
Purity:
99.20
CAS Number:
[1370256-78-2]
Formula:
C25H27N7O3S2
Target:
Apoptosis,c-Kit,FLT3
Application Notes:
MCE Product type: Reference compound
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