Lenalidomide-acetylene-C5-COOH (compound 43, Cereblon ligand-linker Conjugate) is the Lenalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Lenalidomide-acetylene-C5-COOH can be connected to the ligand for protein by a linker to form PROTAC[1]. Lenalidomide-acetylene-C5-COOH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Molecular Weight:
382.41
Purity:
99.26
CAS Number:
[2429878-72-6]
Formula:
C21H22N2O5
Target:
E3 Ligase Ligand-Linker Conjugates
Application Notes:
MCE Product type: Reference compound
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