Bisindolylmaleimide VIII, CAS [[125313-65-7]] Preis auf Anfrage

Product Overview

• Article Name: Bisindolylmaleimide VIII, CAS [[125313-65-7]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-129624
• Supplier Catalog Number: HY-129624
• Alternative Catalog Number: MCE-HY-129624-1UNIT
• Manufacturer: MedchemExpress
• Category: Biochemikalien
• Alternative Names: Ro 31-7549, Bis VIII

Product Description

Bisindolylmaleimide VIII (Ro 31-7549) is a potent and selective protein kinase C (PKC) inhibitor with an IC50 of 158 nM for rat brain PKC. Bisindolylmaleimide VIII has IC50s of 53, 195, 163, 213, and 175 nM for PKC-alpha, PKC-betaI, PKC-betaII, PKC-gamma, PKC-epsilon, respectively[1]. Bisindolylmaleimide VIII facilitates Fas-mediated apoptosis and inhibits T cell-mediated autoimmune diseases[1][2].

Product Properties

• Molecular Weight: 398.46
• CAS Number: [125313-65-7]
• Formula: C24H22N4O2
• Target: Apoptosis,PKC

Application Notes

• Application Notes: MCE Product type: Reference compound1