Bisindolylmaleimide VIII (acetate), CAS [[138516-31-1]]

Product Overview

• Article Name: Bisindolylmaleimide VIII (acetate), CAS [[138516-31-1]]
• Biozol Catalog Number: MCE-HY-129624A
• Supplier Catalog Number: HY-129624A
• Alternative Catalog Number: MCE-HY-129624A-25MG,MCE-HY-129624A-5MG,MCE-HY-129624A-50MG,MCE-HY-129624A-10MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien
• Alternative Names: Ro 31-7549 (acetate), Bis VIII (acetate)

Product Description

Bisindolylmaleimide VIII acetate (Ro 31-7549 acetate) is a potent and selective protein kinase C (PKC) inhibitor with an IC50 of 158 nM for rat brain PKC. Bisindolylmaleimide VIII acetate has IC50s of 53, 195, 163, 213, and 175 nM for PKC-alpha, PKC-betaI, PKC-betaII, PKC-gamma, PKC-epsilon, respectively[1]. Bisindolylmaleimide VIII acetate facilitates Fas-mediated apoptosis and inhibits T cell-mediated autoimmune diseases[2].

Product Properties

• Molecular Weight: 458.51
• Purity: 99.68
• CAS Number: [138516-31-1]
• Formula: C26H26N4O4
• Target: Apoptosis,PKC

Application Notes

• Application Notes: MCE Product type: Reference compound