Withanone is an active ingredient from the roots of Withania somnifera and a GRP75 inhibitor. Withanone has multifunctional neuroprotective effects in alleviating cognitive dysfunction. In neuron-like cells, Withanone can inhibit NMDA-induced excitotoxicity. Withanone can inhibit white adipose tissue browning by blocking the formation of the GRP75-ANT2-UCP1 complex, thereby alleviating cancer-related cachexia. Withanone can be used in the research of tumors and nervous system diseases[1][2][3].
Molecular Weight:
470.60
Purity:
93.28
CAS Number:
[27570-38-3]
Formula:
C28H38O6
Target:
iGluR
Application Notes:
MCE Product type: Natural Products
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