16(R)-AFP 07 (free acid), CAS [[773825-80-2]] Preis auf Anfrage

Product Overview

• Article Name: 16(R)-AFP 07 (free acid), CAS [[773825-80-2]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-129922
• Supplier Catalog Number: HY-129922
• Alternative Catalog Number: MCE-HY-129922-1UNIT
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

Prostaglandin I2 is an unstable prostanoid which, through the 'I prostanoid (IP) receptor, inhibits platelet aggregation and promotes vasodilatation in pulmonary vascular beds. AFP 07 is a 7,7-difluoroprostacyclin derivative that acts as a selective and highly potent agonist for the IP receptor (Ki=0.561 nM).1 AFP 07 shows weaker affinity for EP receptors, with Ki values > 100 nM for EP1-3 and > 10 nM for EP4. 16(R)-AFP 07 is an epimer of AFP 07. Its biological properties, particularly through the IP and EP receptors, remain to be evaluated.

Product Properties

• Molecular Weight: 412.47
• CAS Number: [773825-80-2]
• Formula: C22H30F2O5
• Target: Prostaglandin Receptor

Application Notes

• Application Notes: MCE Product type: Reference compound