MsbA-IN-6 is a potent inhibitor of MsbA. MsbA-IN-6 is an antibiotic. Gram-negative ATP-binding cassette (ABC) transporter MsbA, an essential inner membrane protein, transports lipopolysaccharide from the inner leaflet to the periplasmic face of the inner membrane. MsbA-IN-6 kills Escherichia coli through inhibition of its ATPase and transport activity, with no loss of activity against clinical multidrug-resistant strains[1][2].
Molecular Weight:
451.35
CAS Number:
[2909443-13-4]
Formula:
C24H20Cl2N4O
Target:
Antibiotic,Bacterial
Application Notes:
MCE Product type: Reference compound
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