Quizartinib-d8, CAS [[1300734-19-3]] Preis auf Anfrage

Product Overview

• Article Name: Quizartinib-d8, CAS [[1300734-19-3]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-13001S
• Supplier Catalog Number: HY-13001S
• Alternative Catalog Number: MCE-HY-13001S-1UNIT
• Manufacturer: MedchemExpress
• Category: Biochemikalien
• Alternative Names: AC220-d8, AC708-d8

Product Description

Quizartinib-d8 (AC220-d8) is deuterium labeled Quizartinib. Quizartinib (AC220) is an orally active, highly selective and potent second-generation type II FLT3 tyrosine kinase inhibitor, with a Kd of 1.6 nM. Quizartinib inhibits wild-type FLT3 and FLT3-ITD autophosphorylation in MV4-11 cells with IC50s of 4.2 and 1.1 nM, respectively. Quizartinib can be linked to the VHL ligand via an optimized linker to form a PROTAC FLT3 degrader. Quizartinib induces apoptosis[1].

Product Properties

• Molecular Weight: 568.72
• CAS Number: [1300734-19-3]
• Formula: C29H24D8N6O4S
• Target: Apoptosis,FLT3,Isotope-Labeled Compounds,Ligands for Target Protein for PROTAC

Application Notes

• Application Notes: MCE Product type: Isotope-Labeled Compounds