Torin 2 is an mTOR inhibitor with EC50 of 0.25 nM for inhibiting cellular mTOR activity, and exhibits 800-fold selectivity over PI3K (EC50: 200 nM). Torin 2 also inhibits DNA-PK with an IC50 of 0.5 nM in the cell free assay. Torin 2 can suppress both mTORC1 and mTORC2.
Molecular Weight:
432.40
Purity:
99.65
CAS Number:
[1223001-51-1]
Formula:
C24H15F3N4O
Target:
Apoptosis,Autophagy,DNA-PK,mTOR
Application Notes:
MCE Product type: Reference compound
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