QO-40, a pyrazolo[1,5-a]pyrimidine-7(4H)-one (PPO) derivative, is a KCNQ2/KCNQ3 K+ channels activator with an EC50 of 6.94 µM. QO-40 stimulated Ca2+-activated K+ current (IK(Ca)) with an EC50 value of 2.3 µM in pituitary GH3 lactotrophs[1][2].
Molecular Weight:
377.75
Purity:
98.77
CAS Number:
[1259536-70-3]
Formula:
C18H11ClF3N3O
Target:
Potassium Channel
Application Notes:
MCE Product type: Reference compound
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