Alectinib-d8, CAS [[1256585-15-5]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-13011S
Supplier Catalog Number:
HY-13011S
Alternative Catalog Number:
MCE-HY-13011S-1MG
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Alternative Names:
CH5424802-d8, RO5424802-d8, AF802-d8
Alectinib-d8 is the deuterium labeled Alectinib. Alectinib (CH5424802) is a potent, selective, and orally available ALK inhibitor with an IC50 of 1.9 nM and a Kd value of 2.4 nM (in an ATP-competitive manner), and also inhibits ALK F1174L and ALK R1275Q with IC50s of 1 nM and 3.5 nM, respectively[1]. Alectinib demonstrates effective central nervous system (CNS) penetration[2].
