RepSox (E-616452) is a potent and selective transforming growth factor-beta receptor I/activin like kinase 5 (TGF-beta-RI/ALK5) inhibitor. RepSox inhibits ALK5 autophosphorylation with an IC50 value of 4 nM. RepSox can be used for the research of obesity and associated metabolic diseases such as type 2 diabetes[1][2].
Molecular Weight:
287.32
Purity:
99.92
CAS Number:
[446859-33-2]
Formula:
C17H13N5
Target:
Organoid,TGF-beta Receptor
Application Notes:
MCE Product type: Reference compound
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