Cabozantinib, CAS [[849217-68-1]] Preis auf Anfrage

Product Overview

• Article Name: Cabozantinib, CAS [[849217-68-1]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-13016
• Supplier Catalog Number: HY-13016
• Alternative Catalog Number: MCE-HY-13016-200MG,MCE-HY-13016-100MG,MCE-HY-13016-50MG,MCE-HY-13016-5MG,MCE-HY-13016-10MG,MCE-HY-13016-500MG,MCE-HY-13016-10MMX1ML
• Manufacturer: MedchemExpress
• Category: Biochemikalien
• Alternative Names: XL184, BMS-907351

Product Description

Cabozantinib is a potent and orally active inhibitor of VEGFR2 and MET, with IC50 values of 0.035, and 1.3 nM, respectively. Cabozantinib displays strong inhibition of KIT, RET, AXL, TIE2, and FLT3 (IC50=4.6, 5.2, 7, 14.3, and 11.3 nM, respectively). Cabozantinib shows antiangiogenic activity. Cabozantinib disrupts tumor vasculature and promotes tumor and endothelial cell apoptosis[1][2].

Product Properties

• Molecular Weight: 501.51
• Purity: 99.96
• CAS Number: [849217-68-1]
• Formula: C28H24FN3O5
• Target: Apoptosis,c-Kit,c-Met/HGFR,FLT3,TAM Receptor,VEGFR

Application Notes

• Application Notes: MCE Product type: Reference compound