DS18561882 is a highly potent, isozyme-selective methylenetetrahydrofolate dehydrogenase 2 (MTHFD2) inhibitor with an IC50 value of 0.0063 µM. DS18561882 also has inhibitory effect on MTHFD1 (IC50=0.57 µM). DS18561882 exhibits a good oral pharmacokinetic profile[1].
Molecular Weight:
608.63
Purity:
99.87
CAS Number:
[2227149-22-4]
Formula:
C28H31F3N4O6S
Target:
Methylenetetrahydrofolate Dehydrogenase (MTHFD)
Application Notes:
MCE Product type: Reference compound
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