HDAC/HSP90-IN-2, CAS [[2244714-45-0]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-130274
Supplier Catalog Number:
HY-130274
Alternative Catalog Number:
MCE-HY-130274-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
HDAC/HSP90-IN-2 (compound 26) is a potent dual inhibitor of HDAC (IC50 = 360 nM) and HSP90 (HSP90alpha IC50 = 77 nM). HDAC/HSP90-IN-2 induces HSP70 expression, downregulates HSP90 client proteins, and promotes acetylation of alpha-tubulin and histone H3 in cancer cells. HDAC/HSP90-IN-2 reduces PD-L1 expression in IFN-gamma treated H1975 cells. HDAC/HSP90-IN-2 can be used for cancer research, such as lung and colon cancer[1].
Molecular Weight:
485.57
CAS Number:
[2244714-45-0]
Formula:
C26H35N3O6
Target:
HDAC,HSP,Microtubule/Tubulin,PD-1/PD-L1
Application Notes:
MCE Product type: Reference compound
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