Palbociclib-propargyl is a ligand for target protein CDK6 for PROTAC, and binds to CRBN ligand via a PEG linker to make a PROTAC CP-10. CP-10 shows a DC50 of 2.1 nM for CDK6[1]. Palbociclib-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Molecular Weight:
485.58
Purity:
96.12
CAS Number:
[2366269-23-8]
Formula:
C27H31N7O2
Target:
Ligands for Target Protein for PROTAC
Application Notes:
MCE Product type: Reference compound
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