PROTAC BCR-ABL1 ligand 1, compound GMB-475, is the ligand of PROTAC that allosterically targets BCR-ABL1 protein and recruits the E3 ligase Von Hippel-Lindau, resulting in ubiquitination and subsequent degradation of BCR-ABL1[1].
Molecular Weight:
347.29
Purity:
99.17
CAS Number:
[2489876-34-6]
Formula:
C17H12F3N3O2
Target:
Bcr-Abl,Ligands for Target Protein for PROTAC
Application Notes:
MCE Product type: Reference compound
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