(+)-JQ-1 (JQ1), a chemical probe, is a potent, specific, and reversible BET bromodomain inhibitor, with IC50s of 77 and 33 nM for the first and second bromodomain (BRD4(1/2))[1]. (+)-JQ-1 also activates autophagy[2].
Molecular Weight:
456.99
Purity:
99.90
CAS Number:
[1268524-70-4]
Formula:
C23H25ClN4O2S
Target:
Autophagy,Epigenetic Reader Domain,Ligands for Target Protein for PROTAC
Application Notes:
MCE Product type: Reference compound
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