2-Linoleoyl glycerol (2-Monolinolein, 2-Monolinoleoylglycerol) is a monoacylglycerol that is an antagonist and partial agonist at the type 1 cannabinoid CB1 receptor. The potency of 2-Linoleoyl glycerol can be enhanced by JZL195 (HY-15250), an inhibitor of FAAH and MAGL, and inhibited by the CB1 antagonist AM251 (HY-15443) and Cannabidiol. As a CB1 antagonist, 2-Linoleoyl glycerol does not enhance, but only attenuates, the activity of the CB1/CB2 receptor ligands cannabinoids (AEA) and 2-arachidonoylglycerol (2-AG)[1][2].
Molecular Weight:
354.52
Purity:
99.9
CAS Number:
[3443-82-1]
Formula:
C21H38O4
Target:
Cannabinoid Receptor
Application Notes:
MCE Product type: Reference compound1
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