Emamectin B1a, CAS [[121124-29-6]] Preis auf Anfrage

Product Overview

• Article Name: Emamectin B1a, CAS [[121124-29-6]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-130349
• Supplier Catalog Number: HY-130349
• Alternative Catalog Number: MCE-HY-130349-1MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien
• Alternative Names: L-656,748

Product Description

Emamectin B1a (L-656,748) is a semisynthetic derivative of avermectin B1a that binds to GABA receptors (Ki=17.6 nM in rat brain membranes) and enhances GABA responses. Emamectin B1a acitivates GABAA receptors alpha1beta1gamma2, alpha1beta2gamma2, and alpha1beta3gamma2 with IC50s of 57, 210, and 49.8 nM, respectively. Emamectin B1a also binds to glycine receptors, inhibiting glycine receptors with an IC50=218 nM in rat spinal cord. Emamectin B1a (1.067 ng/mL) caused 90% mortality of S. exigua larvae in foliar spray bioassays and topical application, making it more toxic than avermectin B1.

Product Properties

• Molecular Weight: 886.12
• CAS Number: [121124-29-6]
• Formula: C49H75NO13
• Target: GABA Receptor

Application Notes

• Application Notes: MCE Product type: Reference compound