PDDHV is a calcium absorption inducer and may achieve 45Ca2+ influx by stimulating vanillic acid receptor VR1. PDDHV induces 45Ca2+ uptake (EC50: 70 nM) in rat dorsal root ganglion neurons (expressing native vanilloid receptors) and calcium mobilization (EC50: 125 nM) in VR1-transfected CHO cells. PDDHV also inhibits [3H]-resiniferatoxin (RTX) binding to the dorsal root ganglion membrane in rats[1].
Molecular Weight:
837.09
CAS Number:
[179469-40-0]
Formula:
C49H72O11
Target:
Calcium Channel
Application Notes:
MCE Product type: Reference compound
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