Fostamatinib (R788) disodium hexahydrate is the oral proagent of the active compound R406[1]. R406 is an orally available and competitive Syk/FLT3 inhibitor with a Ki of 30 nM and an IC50 of 41 nM[2]. R406 also inhibits Lyn (IC50=63 nM) and Lck (IC50=37 nM)[3].
Molecular Weight:
732.51
Purity:
99.51
CAS Number:
[914295-16-2]
Formula:
C23H36FN6Na2O15P
Target:
FLT3,Syk
Application Notes:
MCE Product type: Reference compound
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