5beta,6beta-epoxycholestanol is an oxidative metabolite of cholesterol formed by free-radical and non-radical oxidation of cholesterol at the 5,6 double bond. Induces lactate dehydrogenase (LDH) release and apoptosis in macrophage-differentiated U937 cells. Cholesterol 5beta,6beta-epoxide has been found in human fatty streaks and advanced atherosclerotic lesions, but not in normal aortic tissue[1][2][3].
Molecular Weight:
402.65
Purity:
99
CAS Number:
[4025-59-6]
Formula:
C27H46O2
Target:
Biochemical Assay Reagents
Application Notes:
MCE Product type: Biochemical Assay Reagents
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