beta-Spaglumic acid (beta-NAAG) is a competitive NAAG peptidase inhibitor (Ki=1 µM) that protects spinal cord neurons from excitotoxicity and hypoxic damage. beta-Spaglumic acid is also a selective mGluR3 antagonist (mGluR3 receptor functions to regulate activity-dependent synaptic potentiation in the hippocampus). beta-Spaglumic acid can be used in neuroprotection-related studies[1][2].
Molecular Weight:
304.25
Purity:
99.97
CAS Number:
[4910-46-7]
Formula:
C11H16N2O8
Target:
Aminopeptidase,mGluR
Application Notes:
MCE Product type: Reference compound
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