7-Hydroxymethotrexate sodium is a major metabolite of Methotrexate (HY-14519). Methotrexate, an antimetabolite and antifolate agent, inhibits the enzyme dihydrofolate reductase, thereby preventing the conversion of folic acid into tetrahydrofolate, and inhibiting DNA synthesis[1][2].
Molecular Weight:
536.38
Formula:
C20H19N8Na3O6
Target:
Drug Metabolite
Application Notes:
MCE Product type: Reference compound
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