ADX-47273 is a potent, selective and brain-penetrant mGluR5 positive allosteric modulator (PAM), with an EC50 of 0.17 µM for potentiation of glutamate (50 nM) response. ADX-47273 has antipsychotic and procognitive activities[1][2].
Molecular Weight:
369.36
Purity:
99.94
CAS Number:
[851881-60-2]
Formula:
C20H17F2N3O2
Target:
mGluR
Application Notes:
MCE Product type: Reference compound1
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