MS432 is a first-in-class and highly selective PD0325901-based von Hippel-Lindau-recruiting PROTAC degrader for MEK1 and MEK2. MS432 displays good plasma exposure in mice, exhibiting DC50 values of 31 nM and 17 nM for MEK1, MEK2 in HT29 cells respectively[1].
Molecular Weight:
1076.06
Purity:
99.72
CAS Number:
[2672512-44-4]
Formula:
C50H65F3IN7O6S
Target:
MEK,PROTACs
Application Notes:
Reference compound
* VAT and and shipping costs not included. Errors and price changes excepted